Publicaciones relevantes

2023 - Outcomes and clinical characteristics of the compassionate use of plitidepsin for immunocompromised adult patients with COVID-19 .José Aguareles 1, Paula Villares Fernández 2, María Maravillas Carralón-González 3, Carles Forné Izquierdo 4, Eva María Martí-Ballesteros 5, Virginia Pradillo Fernández 5, Gabriel Sotres-Fernandez 3, Teresa García-Delangue 6, Rocío García de Viedma LaPetra 3, María Dolores Sánchez-Manzano 3, Carolina Gutiérrez 7, Marta García-Coca 8, Daniel Carnevali-Ruiz 3, Ruth Barr

2022 - Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses. Nadia Madrid-Elena 1 2, Sergio Serrano-Villar 1 2 3, Carolina Gutiérrez 1 2, Beatriz Sastre 4 5, Matías Morín 6 7, Laura Luna 1 2, Laura Martín 8, Javier Santoyo-López 9, María Rosa López-Huertas 10, Elena Moreno 1 2, María Laura García-Bermejo 8, Miguel Ángel Moreno-Pelayo 6 7, Santiago Moreno

2021 - Fecal microbiota transplantation in HIV: A pilot placebo-controlled study. Sergio Serrano-Villar 1, Alba Talavera-Rodríguez 2, María José Gosalbes 3 4, Nadia Madrid 5, José A Pérez-Molina 5, Ryan J Elliott 6, Beatriz Navia 7, Val F Lanza 2, Alejandro Vallejo 5, Majdi Osman 6, Fernando Dronda 5, Shrish Budree 6, Javier Zamora 8, Carolina Gutiérrez 5, Mónica Manzano 7, María Jesús Vivancos 5, Raquel Ron 5, Javier Martínez-Sanz 5, Sabina Herrera 5, Uxua Ansa 5, Andrés Moya 3 9, Santiago Moreno

2021 - Effect of the use of Galectin-9 and blockade of TIM-3 receptor in the latent cellular reservoir of HIV-1. Marta Sanz; Nadia Madrid-Elena; Sergio Serrano-Villar; Alejandro Vallejo; Carolina Gutiérrez; Santiago Moreno

2020 - Prolonged administration of maraviroc reactivates latent HIV in vivo but it does not prevent antiretroviral-free viral rebound. María Rosa López-Huertas; Carolina Gutiérrez; Nadia Madrid-Elena; Beatriz Hernández-Novoa; J Olalla-Sierra; Montserrat Plana; Rafael Delgado; Rafael Rubio; María Angeles Muñoz-Fernández; Santiago Moreno.

2020 - Maraviroc reactivates HIV with potency similar to that of other latency reversing drugs without inducing toxicity in CD8 T cells. María Rosa López-Huertas; Laura Jiménez-Tormo; Nadia Madrid-Elena; Carolina Gutiérrez; María Jesús Vivancos; Laura Luna; Santiago Moreno.

2020 - Selective miRNA Modulation Fails to Activate HIV Replication in In Vitro Latency Models María Rosa Lopez-Huertas; Matias Morin; Nadia Madrid-Elena; Carolina Gutiérrez; Laura Jiménez-Tormo; Javier Santoyo; F Sanz-Rodriguez; Miguel Angel Moreno-Pelayo; Laura Garcia-Bermejo; Santiago Moreno.

2019 - High CD8 T cell percentage and HCV replication control are common features in HIV-1 controllers and HTLV-2-co-infected patients with a history of injection drug use. E Ruiz-Mateos; MJ Ruiz-León; L Tarancón-Díez; C Gutiérrez; F Dronda; B Domínguez-Molina; MJ Pérez-Elías; A Moreno; M Leal; S Moreno; A Vallejo.

2019 - Analysis of the dysregulation between regulatory B and T cells (Breg and Treg) in human immunodeficiency virus (HIV)-infected patients C Gutiérrez; J Lopez-Abente; V Pérez-Fernández; A Prieto-Sánchez; R Correa-Rocha; S Moreno; MA Muñoz-Fernández; M Pion.

2018 - D72/CD100 and PD-1/PD-L1 markers are increased on T and B cells in HIV-1+ viremic individuals, and CD72/CD100 axis is correlated with T-cell exhaustion.R Correa-Rocha; J Lopez-Abente; C Gutiérrez; VA Pérez-Fernández; A Prieto-Sánchez; S Moreno; MA Muñoz-Fernández; M Pion.

2018 - Effects of Immunonutrition in Advanced HIV Disease: a Randomized Placebo Controlled Clinical Trial (Promaltia Study).Sergio Serrano-Villar; M de Lagarde; J Vázquez-Castellanos; A Vallejo; JI Bernardino; N Madrid-Elena; M Matarranz; A Díaz de Santiago; C Gutiérrez; A Cabello; J Villar-García; JR Blanco; O Bisbal; T Sainz; A Moya; S Moreno; MJ Gosalbes; V Estrada

2018 - Maraviroc is associated with latent HIV-1 reactivation through NF-?B activation in resting CD4+ T cells from HIV-Infected Individuals on Suppressive Antiretroviral Therapy. Nadia Madrid-Elena; María Laura García-Bermejo; Sergio Serrano-Villar; Alberto Díaz de Santiago; Beatriz Sastre; Carolina Gutiérrez; Fernando Dronda; María Coronel-Díaz; Ester Domínguez; María Rosa López-Huertas; Beatriz Hernéndez-Novoa; Santiago Moreno.

2017 - The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1. María Rosa López-Huertas; Laura Jiménez-Tormo; Nadia Madrid-Elena; Carolina Gutiérrez; Sara Rodriguez-Mora; Maite Coiras; José Alcamí; Santiago Moreno

2016 - Changes in the immune response after treatment with benznidazole versus no treatment in patients with chronic indeterminate Chagas disease. Alejandro Vallejo; Begoña Monge-Maillo; Carolina Gutierrez; Francesca Norman; Rogelio Lopez-Velez; Jose Antonio Perez-Molina.

2016 - Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy. Carolina Gutiérrez; Sergio Serrano-Villar; Nadia Madrid-Elena; María Jesús Pérez-Elías; María Elena Martín; Coral Barbas; Javier Ruiperez; Eduardo Muñoz; María Ángeles Muñoz-Fernández; Trevor Castor; Santiago Moreno

2015 - Expression on Gut Homing Beta 7 receptor on T cells: surrogate marker for microbial translocation in suppress HIV-1 infected patients?. María Abad Fernández; Carolina Gutiérrez Montero; Nadia Madrid Elena; Beatriz Hernández Novoa; Laura Díaz; María Ángeles Muñoz Fernández; Santiago Moreno Guillén; Alejandro Vallejo Tiller.

2015 - [Is it possible to cure HIV infection?] Carolina Gutiérrez; Nadia P Madrid; Santiago Moreno.

2013 - Correlation between different methods to measure microbial translocation and its association with immune activation in long-term suppressed HIV-1-infected individuals María Abad Fernández; Alejandro Vallejo; Beatriz Hernández Novoa; Laura Díaz; Carolina Gutiérrez; Nadia Madrid; María Angeles Muñoz; Santiago Moreno

2013 - Dynamics of the HIV-1 latent reservoir after discontinuation of the intensification of antiretroviral treatment: results of two clinical trials. Carolina Gutiérrez; Beatriz Hernández Novoa; Alejandro Vallejo; Sergio Serrano Villar; María Abad Fernández; Nadia Madrid; Laura Díaz; Ana Moreno; Fernando Dronda; Javier Zamora; María Angeles Muñoz Fernández; Santiago Moreno

2013 - he CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression. Sergio Serrano Villar; Carolina Gutiérrez; Alejandro Vallejo; Beatriz Hernández Novoa; Laura Díaz; María Abad Fernández; Nadia Madrid; Fernando Dronda; Javier Zamora; María Ángeles Muñoz Fernández; Santiago Moreno

2013 - Prevalence of primary resistance mutations to integrase inhibitors in treatment-naïve and -experienced patients infected with B and non-B HIV-1 variants. Carolina Gutiérrez; Beatriz Hernández Novoa; María Jesús Pérez Elías; Ana María Moreno; Africa Holguín; Fernando Dronda; José Luis Casado; Santiago Moreno

2012 - he effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients. Alejandro Vallejo; Carolina Gutierrez; Beatriz Hernandez Novoa; Laura Diaz; Nadia Madrid; María Abad Fernandez; Fernando Dronda; María J Perez Elias; Javier Zamora; Eduardo Muñoz; María A Muñoz Fernandez; Santiago Moreno

2012 - inical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy. ilberto Betancor; César Garriga; Maria C Puertas; María Nevot; Lourdes Anta; José L Blanco; M Jesús Pérez Elías; Carmen de Mendoza; Miguel A Martínez; Javier Martinez Picado; Luis Menéndez Arias; José Antonio Iribarren; Estrella Caballero; Esteban Ribera; Jos

2011 - Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected. Carolina Gutiérrez; Laura Díaz; Alejandro Vallejo; Beatriz Hernández Novoa; María Abad; Nadia Madrid; Viktor Dahl; Rafael Rubio; Ana M Moreno; Fernando Dronda; José Luis Casado; Enrique Navas; María Jesús Pérez Elías; Javier Zamora; Sarah Palmer; Eduardo Muñoz; María Ángeles Muñoz Fernández; Santiago Moreno

2008 - Effect of food on the antiviral activity of didanosine enteric-coated capsules: a pilot comparative study. Beatriz Hernández Novoa; Antonio Antela; Carolina Gutiérrez Montero; José Antonio Pérez Molina; Fernando Ronda Núñez; María Jesús Pérez-Elías; José Luis Casado Osorio; Carmen Page Alonso; María Belén Pumares Álvarez; Juan Carlos Galán; Santiago Moreno Guillén

2005 - Analysis of Quantitative PCR assay for CMV infection in liver transplant recipients: and intent to find the optimal cut-off value. P Martin-Davila, J Fortun, C Gutiérrez, P Marti-Belda, A Candelas, A Honrubia, R Barcena, A Martinez, A Puente, E Vicente, S Moreno

2005 - Surveillance of drug resistance and HIV subtypes in newly diagnosed patients in Spain during 2004. Martinez-Picado J, Gutiérrez C, de Mendoza C et al

2005 - Impact of drug resistance genotypes on CD4+ counts and plasma viremia in heavily antiretroviral-experienced HIV-infected patients.Berta Rodes; Federico García; Carolina Gutierrez; Javier Martinez Picado; Antonio Aguilera; Maria Saumoy; Alex Vallejo; Pere Domingo; David Dalmau; Maria Angels Ribas; José Luis Blanco; José Pedreira; Maria Jesús Perez Elias; Manuel Leal; Carmen de Mendoza; Vincent Soriano

2005 - High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir. Maria Jesús Pérez Elías; Santiago Moreno; Carolina Gutiérrez; Dolores López; Victor Abraira; Ana Moreno; Fernando Dronda; Jóse Luis Casado; Antonio Antela; Miguel Angel Rodríguez

2005 - Evidence for preferential genotyping of a minority human immunodeficiency virus population due to primer-template mismatching during PCR-based amplification. Javier Martinez Picado; Kristina Morales Lopetegi; Cristina Villena; Carolina Gutiérrez; Nuria Izquierdo; Silvia Marfil; Bonaventura Clotet; Lidia Ruiz

2004 - Higher virological effectiveness of NNRTI-based antiretroviral regimens containing nevirapine or efavirenz compared to a triple NRTI regimen as initial therapy in HIV-1-infected adults. María Jesús Pérez Elías; Ana Moreno; Santiago Moreno; Dolores López; Antonio Antela; José Luis Casado; Fernando Dronda; Carolina Gutiérrez; Carmen Quereda; Enrique Navas; Víctor Abraira; Miguel Angel Rodríguez

2004 - Resistencias a Tenofovir DF: aspectos básicos y clínicos. Santiago Moreno, Maria Jesús PérezElías, Carolina Gutiérrez

2003 - Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV1. S Moreno, JL Casado, MJ Perez-Elias, F Dronda, A Antela, A Moreno, C Gutiérrez

1999 - Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. ose L. Casado, Julio Arrizabalaga, Milagros Montes, Paloma Marti-Belda, Cristina Tural, Javier Pinilla, Carolina Gutiérrez, Joseba Portu, Rob Schuurman and Koldo Aguirrebengoa for the Spanish CMV-AIDS Study Group

2010 - Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database. Poveda E, Anta L, Blanco JL, PérezElías MJ, García F, Leal M, Ribera E, Gutiérrez F, Soriano V, de Mendoza C; Resistance Platform of the Spanish AIDS Research Network (ResRIS; miembro del Study Group, C Gutiérrez).

2009 - HIV-1 reverse transcriptase thumb subdomain polymorphins associated with virological failure to nucleoside drug combinations.C Garriga, MJ Pérez-Elías, R Delgado, L Ruiz, L Pérez-Álvarez, T Pumarola, Ana López-Lirola, Juan González-García and L Menéndez-Arias on behalf of the Spanish Group for the Study of Antirretroviral Drug Resistance (member of the Study Group, C Gutiérrez.

2012 - Sensitivity of seven HIV subtyping tools differs among subtypes/recombinants in the Spanish cohort of naïve HIV-infected patients (CoRIS). Gonzalo Yebra; Miguel de Mulder; Leticia Martín; Santiago Pérez Cachafeiro; Carmen Rodríguez; Pablo Labarga; Federico García; Cristina Tural; Angels Jaén; Gemma Navarro; A Holguín. Resistance Platform of the Spanish AIDS Research Network (ResRIS; miembro del Study Group, C Gutiérrez).

2012 - Most HIV type 1 non-B infections in the Spanish cohort of antiretroviral treatment-naïve HIV-infected patients (CoRIS) are due to recombinant viruses. Gonzalo Yebra; Miguel de Mulder; Leticia Martín; Carmen Rodríguez; Pablo Labarga; Isabel Viciana; Juan Berenguer; María Remedios Alemán; Juan Antonio Pineda; Federico García; Africa Holguí. Resistance Platform of the Spanish AIDS Research Network (ResRIS; miembro del Study Group, C Gutiérrez).